Bindyu A. Prevention and treatment of intraoperative complications in clipping brain aneurysms

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U100206

Applicant for

Specialization

  • 222 - Медицина

27-01-2021

Specialized Academic Board

ДФ 26.557.001

State Institution "Academician AP Romodanov Institute of Neurosurgery of the National Academy of Medical Sciences of Ukraine"

Essay

The dissertation work is devoted to the decision of an actual scientific and applied problem of neurosurgery - improvement of treatment of patients with intraoperative complications at clipping of brain aneurysms. The aim of the study was to develop a comprehensive system of measures for the prevention and treatment of intraoperative complications to improve the results of surgical treatment of brain aneurysms. Acute cerebrovascular accident (ACVA) by type of hemorrhage is a characteristic manifestation of ruptures of arterial aneurysms (AA) of the brain, surgical treatment of which currently has no alternatives. The ultimate success of the treatment of aneurysmal brain disease at the stage of clinical manifestations, which as a mandatory component includes maintaining quality of life, depends on the uncomplicated performance of operations aimed at "excluding" the aneurysm from the cerebral circulation. Intraoperative complications (IOC) during transcranial interventions are the cause of persistent mortality and disability in patients with AA of the brain. Among the complications of surgical treatment, the most unpredictable and dangerous is the repeated, so-called intraoperative rupture of the aneurysm (IORA), the patterns of which, hemodynamic manifestations and clinical consequences require in-depth study, systematization, development of prevention and treatment. The presented dissertation research is devoted to these aspects of the problem of AA of the brain treatment, which are relevant for vascular neurosurgery.

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