Kovtun A. Rearrangements of spiro derivatives as a method of synthesis of new luminofors

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U102701

Applicant for

Specialization

  • 102 - Хімія

26-11-2021

Specialized Academic Board

ДФ 08.078.008

Ukrainian State University of Chemical Technology

Essay

The dissertation is devoted to the synthesis and research of photophysical properties of previously unknown phosphors, which contain a xanthene fragment in their structure, as well as to the study of the interaction of spiro derivatives benzothienopyrimidines with electrophilic agents and the prognosis of their antitumor activity. The relevance of this area of research meets the requirements of modern organic chemistry to study and establish the relationship between the structure and properties of organic molecules. Due to the photophysical characteristics of xanthenes, namely excellent lightfastness, quantum yields, high extinction coefficients and luminescence maxima, low in vivo toxicity and relatively high solubility in water, they are used as light filters, optical fibers, chemosensors to detect small molecules, sensitizers in solar panels and as active substances in dye lasers. The study of the properties of this type of dyes is devoted to a large number of works by scientists from around the world since the twentieth century, but despite progress in this direction, the demand for new spectral properties is not extinguished. Not the least role in this is played by the development of modern technologies in various fields of science, especially in chemistry, biology and medicine.

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