Karpenko K. The use of mini-invasive technologies in the complex treatment of patients with post-thrombotic disease of the lower extremities

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0824U001435

Applicant for

Specialization

  • 222 - Медицина

17-05-2024

Specialized Academic Board

ДФ 26.003.153

Bogomolets National Medical University

Essay

The dissertation is devoted to an actual scientific problem - surgical treatment of patients with post-thrombotic disease of the lower extremities. Post-thrombotic disease is a chronic venous pathology associated with acute deep vein thrombosis (DVT). The name "post-thrombophlebitic syndrome" is found in literary sources of the countries of North America and the countries of the European Union. Postthrombotic disease of the lower extremities (PTDLE) is a pathology caused by further pathomorphological and pathophysiological processes in the venous system. Although the pathogenesis of PTDLE is complex and closely related to deep vein thrombosis and previous deep vein thrombosis, the central role is played by venous hypertension (hydrostatic blood pressure between the right atrium and the foot), PTDLE is detected in 5-7% of the working population of developed countries and up to 28% from patients with various types of venous pathology. PTDLE is the most common long-term complication after deep vein thrombosis that occurs in a limb. In most cases, PTDLE develops from several months to several years after a DVT and is from 1 to 3 per 1000 people in the general population. Operative intervention on the venous system in patients with PTDLE is a difficult stage in complex treatment. Modern operative interventions provide maximum cosmetic effect and complete radicalism regarding the causes of occurrence, differ in methods, techniques and tools. The introduction of mini-invasive technologies and the technology of electric welding of living tissues in the complex treatment of patients with PTDLE is relevant, reducing the duration of inpatient treatment, the severity of the course of the disease, and the risks of complications. The purpose of the study: to improve the results of treatment of patients with PTDLE, through the optimal choice of methods and volumes of surgical interventions based on anatomical and hemodynamic types of the disease and the use of minimally invasive technologies, including new ones implemented based on developed surgical tools.

Research papers

К. В. Гуменюк, І. І. Гангал, К. К. Карпенко. Надання високоспеціалізованої медичної допомоги військовослужбовцям Збройних Сил України мініінвазивними рентгенендоваскулярними методиками // Запорізький медичний журнал. 2021. Т. 23, № 3(126). С. 375-380. DOI: 10.14739/2310-1210.2021.3.223139.

Anatoliy Kazmirchuk, Yurii Yarmoliuk, Igor Lurin, Rostislav Gybalo, Olexandr Burianov, Serhii Derkach, Kostiantyn Karpenko. (2022) Ukraine’s Experience with Management of Combat Casualties Using NATO’s Four-Tier ‘‘Changing as Needed’’ Healthcare System. World J Surg. Volume46, Issue12 https://doi.org/10.1007/s00268-022-06718-3.

Muzychenko P. F.; Сhernyak V. A.; Savosko S. I.; Lankin YU. N.; Karpenko K. K.; Dubenko D. E.; Nahaluk U. V.; Zorgach V. U.; Manzuk T. I.; Gybalo R. V. Koshevskiy U. I. Morphological assessment of vascular anastomoses performed using high frequency electric welding. Int. J. Morphol., 39(4): 2021. Р. 1183-1189.

В.А. Черняк, В.М. Роговський, Ю.В. Нагалюк, Р.В. Гибало, С.В. Дибкалюк, К.К. Карпенко. Лікування наслідків бойових вогнепальних поранень магістральних судин нижніх кінцівок за період 2014-2019 років проведення АТО та ООС. DOI 10.26724/2079-8334-2021-2-76-153-158 // Світ Медицини та Біології. – №2(76). – 2021. – С. 153-158.

Karpenko, K. (2023). Theory and methodology of innovative health care development in the national, European and global contexts: MINI-INVASIVE SURGERY FOR POST-THROMBOTIC DISEASE OF THE LOWER EXTREMITIES (L. Butska, Ed.; 1st ed.). Academy of Silesia. https://doi.org/10.54264/M021

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