Komisarenko I. Differentiated approach to stent placement in minimally invasive treatment of ureteral stones

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0824U001516

Applicant for

Specialization

  • 222 - Медицина

21-05-2024

Specialized Academic Board

ДФ 26.003.167

Bogomolets National Medical University

Essay

To perform this work, we studied the results of treatment of 512 patients with stones in various parts of the ureters, which were divided into several groups, and within each group, subgroups were additionally identified. The first group of 284 (55.5%) patients consisted of patients with uncomplicated ureteral stones. Subgroup 1A consisted of 135 (26.4%) patients who had no complications in the postoperative period, despite the refusal to install a stent. Subgroup 1B consisted of 63 (12.3%) patients with early postoperative complications that occurred after refusal to install a stent, despite the apparent absence of indications for stenting. The next 1B subgroup included 62 (12.1%) patients whose refusal to install a stent was supported by intraluminal ureterometry. And the last subgroup 1G included 24 (4.7%) patients in whom, on the basis of intraluminal ureteromanometry, a decision was made to install a urethral stent for up to 7 days. Group 2 - 175 (34.2%) patients - consisted of patients with complicated ureteral calculi. At the same time, subgroup 2A included 57 (11.1%) patients who had no postoperative complications when the stent was removed within the "standard" timeframe, i.e. 7-10 days after its installation. In 31 (6.1%) patients of subgroup 2B, on the contrary, postoperative complications occurred after stent removal within the same time frame. In 61 (11.9%) patients of subgroup 2B, the stent was removed within the "standard" timeframe based on intraluminal manometry and retrograde ureterography, and in 26 (5.1%) patients of subgroup 2G, based on intraluminal manometry and retrograde ureterography, stent removal was delayed for 14-21 days. Group 3 included 53 (10.4%) patients who underwent laparoscopic ureterolithotomy for ureteral calculi, with 18 (3.5%) patients in subgroup 3A not having a stent placed after surgery, and 35 (6.8%) patients in subgroup 3B having a stent placed. All patients underwent examination radiography of the urinary system, excretory or infusion urography with registration of the image on film, retrograde pyeloureterography, cystography, and spiral CT with bolus contrast on admission to the clinic. Diagnostic methods included ultrasound examination of the kidneys and bladder. Laboratory diagnostic methods included the study of general clinical and biochemical blood parameters in the preoperative period and on days 1-2, as well as on days 3-4, 5-7, 8-10 of the postoperative period.

Research papers

Нікітін ОД, Рощин ЮВ, Комісаренко ІМ, Фуксзон АС, Смехун СІ. Особливості перебігу післяопераційного періоду при стентуванні сечоводу в пацієнтів з ускладненими формами уретеролітіазу. Вісник морської медицини. 2020;4:80-8

Нікітін ОД, Рощин ЮВ, Комісаренко ІМ, Фуксзон АС, Смехун СІ. Можливості бездренажного ведення пацієнтів з неускладненим уретеролітіазом. Здоров'я чоловіка. 2020;4: 32-38.

Нікітін О. Д., Комісаренко І. М. Критерії щодо встановлення стентів при ендоскопічному лікуванні хворих із неускладненими каменями сечоводу. Вісник морської медицини.2023;1:136-142.

Нікітін О. Д., Комісаренко І. М. Вплив стентування сечоводу на післяопераційні результати лікування хворих з ускладненим уролітіазом. Актуальні проблеми транспортної медицини. 2023;4(74):59-67.

Komisarenko I, Banyra O, Nikitin O, Klymenko Y, Chaplia M, Borzhievskyy A. Efficacy of combination therapy tadalafil plus tamsulosin in ureteral stents- related symptoms relief. Cent European J Urol. 2024; 77: 111-116.

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