Akhova O. Cytomorphologycal features of endocrine cells in breast carcinoma

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U001074

Thesis Registration Form

0400U001074.pdf

Applicant for

Specialization

  • 14.01.07 - Онкологія

12-04-2000

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

The thesis is devoted to the studying of histochemical, immunohistochemical and ultrastructural characteristics of endocrine cells (EC) in breast It was found that EC occurred in 35% of BC. Usually these cells were revealed in mucinous carcinomas (50%) and infiltrative glandular carcinomas (33%). It was established that BC with EC, which contained more than 10% of EC of the total tumor cell population were more aggressive than BC with single EC (less than 10%). That was confirmed by the features of histological structures of these BC and also low 5-year survival (61.66(9,6)% of patients compare with the lastgroup (82.23(8,03)%, (p<0.05).

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