Skachek M. Influence of the Ionizing Irradiation on the Hypothalamic-hypophysal-thyroid System and its Modification with the Help of Substances of Natural Origin

The thesis is dedicated to the study of the characteristics of reaction of hypothalamic-hypophysal-thyroid system (HHTS) on the influence of different doses of ionizing irradiation. Comparative characteristics of HHTS reaction have been established experimentally by the results of the influence of radioactive iodine, external X-ray and gamma irradiation in the same dose (5 Gy). It has been established that the reaction of thyroid on influence of external gamma-irradiation in low and medium doses (0,1; 0,5; 1; 2 and 5 Gy) has non-linear dependence. Comparative study has been conducted on the base of total gamma-irradiation, irradiation of head and local irradiation of thyroid. It has been shown that the influence of ionizing irradiation changes response of HHTS on action of pharmaceutical preparations: thyroidin and mercazolil. The cryopowder of calendula has been studied and proposed for use in the confectionery industry.