Khrub K. The blast cell's immunophenotyping in acute leukemias with minimal differentiation sings

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U001816

Applicant for

Specialization

  • 14.01.07 - Онкологія

21-06-2000

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

The dissertation is devoted to problem of diagnostics of acute leukemias (AL) with minimal differentiation sings. This heterogenic category of diseases includes myelogenous AL - M0, M5a, M6 and M7 according FAB-classification; lymphoblastic AL (ALL) with atypical expression of myeloid antigens, the presence of single peroxidase-positive blast cells, asynchronic expression of lymphoid antigens. The principles of differentiative diagnosis are justified. Some new variants of AL - AL from cell-precursors of natural killer, T-ALL with t(2;11), are characterized

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