Osadchuk Z. The role of hereditary susceptibility and environmental risk factors in origin of thyroid gland diseases among children

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U002368

Applicant for

Specialization

  • 14.01.10 - Педіатрія

12-09-2000

Specialized Academic Board

Д 26.553.01

SI «Institute of Pediatrics, Obstetrics and Gynecology named academician O. M. Lukyanovaya NAMS of Ukraine»

Essay

Dissertation is dedicated to the study of prognostical importance of clinical, morphological and immunohistochemical criterions as well as of nuclear protein p53 expression and of proliferating cell nuclear antigen (PCNA) of the diagnostics and course of urothelial bladder cancer. The author has determined the peculiarities of the morphogenesis urothelial bladder cancer of the patients who settle at the radioactive elements free and contaminated territories of Ukraine. The unfavourable morphological and immunohistochemical indications of bladder cancer were defined, which influence its recurrence frequency.

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