Kotenko O. Use of intraoperative crioaction in combined treatment of patients of with rectal cancer

The object of the study: patients with rectal cancer and distal localization of the tumour in combined treatment. The purpose of the study: to improve results of treating patients with cancer in the distal portion of the rectum owing to extension of the indications for sphincter-salvation operations by use of intraoperative cryoinfluence on the tumour. The methods of the study and equipment: general clinical methods, deficit of the circulating blood, immunity, cytological study of wash waters, vascular changes in the blood flow, electron microscope study of cell structures in the tumour, functional, short-term and remote results; use of a cryodestructor, an electrosphincterometer and a rheograph. Theoretical and practical results: the use of the intraoperative cryoinfluence has made it possible to extend indications for sphincter-salvation operations, to improve ablastics of the surgical interventions made, to increase the share of the destructively changed cells. Dynamics of the immune and vascular ab normalities and functional changes depending upon the use of cryoinfluence was studied. The intraoperative cryoinfluence has made it possible to produce a partial effect on the surgical tactics of the rectal cancer, to reduce the risk of perforation of the intestine during its mobilization, to decrease the number of recurrences of the tumour, to increase the average life span. The degree of introduction: new theoretical and practical elaborations; introduction into the work of medical establishments (reports on introduction).