GRUZEVS'KYJ O. The study of species-specificity of Mycobacterium kansasii surface components.

The dissertation is dedicated to the problem of looking for species-specific components of Mycobacterium kansasii. The method of obtaining of mycobacterial surface components in mild conditions is elaborated. The picture of electrophoretic division of Mycobacterium kansasii extracts is studied. Obtained electrophoregrams allow to note 6 characteristic components which could be used for identification of electrophoretic spectrums of Mycobacterium kansasii extracts. Chemical nature and molecular weights of extracts components were studied. The conditions of chromatographic division of extracts into isolated fractions are elaborated. The investigation of fractions antigenic structure was fulfilled. There was revealed that some these fractions contained antigenic components which may be considered as species-specific. Revealed species-specific components could be used for creation of diagnostic test-system.