Samson O. Subclinical hypothyroidism and disturbances of the level of gamma-aminibutyric acid in blood serum of children with tumor and other thyroid pathology.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U001343

Applicant for

Specialization

  • 14.01.14 - Ендокринологія

24-04-2001

Specialized Academic Board

Д 26.558.01

STATE INSTITUTE "V.P. KOMISSARENKO INSTITUTE OF ENDOCRINOLOGY AND METABOLISM OF THE NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE"

Essay

purpose: study of the status of PTS and determination of gamma-aminobutyric acid (GABA) level in blood of child- ren with thyroid disorders (TD), developing a new method developing a new me- of diagnosis of metastases or local recurrences of malignant tumors of thyroid gland (MT TG) in children operated on. Methods and equipment: radioimmunoassay, radiorecepto- assay, fluid scintillating counter. Theoretical and practical outcomes: children with TD have modified GABA- ergic system - activation and untypical her answer on the stimu- lation; diagnostic criteria of the subclinical hypothyroidism has been determined. Innovation: existence of metastases of MT in children operated on may be confirmed by deter- mination of GABA level in blood. Degree ofintroduction: the data can be used for examination of children with MT TG and for the lectures in medical educational institutions. The sphere (area) of use: endocrinology, oncology.

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