Fastovets' O. Clinical-pathogenetic bases of correction of bone metabolism disorders in patients with generalized parodontitis

The results of the structural-functional investigation of bone tissue of jaws and skeleton in 142 healthy and 152 patients with the diagnosis of generalized parodontitis demonstrated the absence of conditionality between systemic osteoporosis and generalized parodontitis. Findings of the biochemical studies of the kinetic indices of calcium and phosphoric homoestasis and the markers of І bone exchange in elected 30 healthy and 184 patients suffered from generalized parodontitis, who had no systemic disturbances of bone tissue's metabolism, have allowed to insist that in the basis of oste рorotic changes in alveolar bone there was heightened osteoresorp- tion which wasn't compensated by normal bone formation. It has been suggested local osteotropic therapy in the complex treatment of the generalized parodontitis The medicinal composition of osteo- genic effect contained chinoxidine, ipriflavone, hydroxiapatite in combination with ultraphonephoresis of remedy prevented resorp- tion-xydifone have been app roved as a concrete therapeutic scheme.