Skrypnyk L. Activity of enzymes of trans-membrane transport and the influence of rehydration therapy on them in the cholera patients

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U001678

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

24-05-2001

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

Dissertation dedicated to pathogenesis of infraction in trans-membrane transport in the El-Tor cholera patients. 90 cholera patients with I, II and III level of dehydration were examined. In the disease dinamics the following was studied in the erythrocytes: the content of diene conjugate (DC), malonic dialdehyde (MDA), reduced shape of hlutathione (GSH), carbothiolic compounds (SS, SH), activity of superoxydysmutase (SOD), catalase, glutathioneperoxidase (GP), glutathionereduktase (GR), glutathionetrasferase (GN), content of NADPH, NADP, activity of Nf , K , Ca -ATPh, content of AMPh, ADPh and ATPh, guanyl nucleotides, activity of adenylatcyclase, guanylatcyclase.

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