Prokopenko V. The elements of stereotype regulation of in vitro DNA transcription by physiologically active compounds

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U001978

Thesis Registration Form

0401U001978.pdf

Applicant for

Specialization

  • 02.00.10 - Біоорганічна хімія

21-06-2001

Specialized Academic Board

Д26.220.01

Essay

Bioregulatory stereotypes of action of physiologically active compounds (FAC). Revealing of bioregulatory stereotypy elements of FAC influence on in vitro transcription. Methods of mathematical modeling, gene engeneering. Spectrometr, electrophoresis, PC. Bioregulatory influence of specific ligands of extracellular receptors on transcription was shown. The elements of a structural community in the groups of blockators and activators have been found. The effective computer system capable to divide of substance on classes correspondingly to their influence on adrenergic and cholinergic receptors was obtained. Sphere of use - bioorganic chemistry, pharmacology.

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