Stepanova N. Substantiation and Efficiency of Systemic Enzyme and Singlet Oxygen Therapy of Patients with Systemic Lupus Erythematosis.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U000179

Thesis Registration Form

0402U000179.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

30-11-2001

Specialized Academic Board

К 29.600.01

Essay

The dissertation is devoted to the problems of improving the efficiency of remedial measures in systemic lupus erythematosis, primarily, to its main visceral manifestations such as lupous glomerulonephritis and lupous pneumonitis. The general efficiency of pathogenetic therapy of patients with systemic lupus erythematosis using a polyfermentative mixture of wobenzym and singlet oxygen has been estimated. The singlet enzymotherapy has been proved to improve the results of acting on the sings of glomerulonephritis, while the singlet oxygen me - on the course of pneumonitis. Wobenzyme used in a complex therapy of lupous glomerulonephritis favourably acts on both laboratory sings of lupous glomerulonephritis (erythrocyturia and b2-microglobulinuria indices) and on the renal function indices (clearence of creatinine, urea, potassium, phosphorus). The impact of the systemic enzymotherapy on the physicochemical state of the urine of patients with lupous glomerulonephritis has been studied according to the fin dings of dynamic interphase tensioreometry. The dynamics of the pulmonang circulation state changes has been determined in patients with pulmonang affection under the influence of singlet oxygen therapy. A necessity for using interphase urine tensioreometry and the expired air moisture condensate to control the effeciency of medical measures in lupous nephritis and pneumonitis has been substantiated

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