Kulik I. Preparations of Fluorine-containing Chiral Blocks and Applications in the Syntheses of the Natural Compound's Analogues

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U001044

Applicant for

Specialization

  • 02.00.10 - Біоорганічна хімія

29-03-2002

Specialized Academic Board

Д 26.220.01

V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Essay

Reaction of fluorination of chiral alcohols. Preparations of fluorine-containing chiral structural blocks and application in the synthesis of natural compound's analogues. Chemical synthesis, physics-chemical methods, spectrometrs, chromatograph. It was proved, that acceptor substituents influence on regio- and stereoresults of reaction fluorination. The methods of asymmetric synthesis of fluorine-containing structures for the preparation of analogues of biologically active substances were developed. Bioorganic and organic chemistry.

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