Romanyuk S. Antigenic and immunobiological properties of diphtheria toxin and its subunits

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U002772

Applicant for

Specialization

  • 02.00.10 - Біоорганічна хімія

27-09-2002

Specialized Academic Board

Д 26.220.01

V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Essay

Diphtheria toxin (DT) and antibody against it. Investigation of antigenic properties of DT and its subunits at the different diphtheria infection forms. Methods of bioorganic chemistry and biochemistry, mathematical modeling, spectrophotometer, device for electrophoresis. Antigenic properties of DT in the children with different diphtheria infection forms were revealed, immunobiological properties, which allow him to counteract the factors of immunological protection. The developed methods can be applied in tests - systems for express-diagnostics of diphtheria. Sphere of use - bioorganic chemistry, medicine.

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