Poroshina T. 3. The HLA phenotype-associated interleukin-2 production and expression of receptors to interleukin-2 in patients with allogenic kidney

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U001540

Applicant for

Specialization

  • 03.00.09 - Імунологія

17-03-2003

Specialized Academic Board

Д 26.003.02

Essay

The dissertation represents the results of studies pointed out the new data about guantitative characteristics of CD3+, CD4+, CD8+, CD16+, CD19+, CD25+, CD3+ DR+ cells of pathology under study. There was substantiated the expediency of dynamic determination of IL-2 production and receptors to IL-2 in patients after renal allograft transplantation, as the additional diagnostic and prognostic criteria of acute allograft rejection (AAR). There was demonstrated the associative relation between HLA antigents, IL-2 production and expression of receptors to IL-2 on cells of peripheric blood in patients with ChRI.

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