Мaystrenko O. Using amixin in the complex therapy of patients with enteroviral meningitis.

The aim of research: increasing the efficiency of the patients with enteroviral meningitis treatment by inclusion amixin in the complex therapy. The object of research: the patients with enteroviral meningitis. The methods of research: general clinical tests; epidemiological, laboratory, immunological, virologic and serological tests It is established, that patients with enteroviral meningitis prior to the beginning of therapy reveal attributes secondary immune deficiency illnesses more expressed at heavy current. In particular, decrease of amount Т-and Вm-lymphocytes, Th-lymphocytes, reduction IRI, deterioration of parameters of phagocytoses, decrease of level IgA in the blood of the patients is marked, insufficient increase of a level of the serum IFN and SPIL and authentic decrease of ability of leukocytes to produce -and -ИФН in vitro in reply to inductors. There were require immune correction. Inclusion of amixin in a complex therapy of patients with enteroviral meningitis promotes reduction of duration of subjective and objective symptoms of disease, decrease the terms of stay the patients in a hospital, reduction of complications and relapses. Positive dynamics of clinical current of enteroviral meningitis at patients, received amixin is accompanied by normalization of all basic parameters cellular and gumoral immunity, renovation the phagocytoses, and also improvement of parameters interferon genesis: increase of a level of the serum IFN and increase of production -and -IFN in vitro by leukocytes.