Byel's'ka L. Investigation of phagocytic brain cells activity in experimental allergic encephalomyelitis and its correction.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U000604

Thesis Registration Form

0404U000604.pdf

Applicant for

Specialization

  • 03.00.09 - Імунологія

05-02-2004

Specialized Academic Board

Д 26.003.02

Essay

The thesis is devoted to an actual problem of neuroimmunology - the investigation of phagocytic brain and spleen cells in functional condition in experimental allergic encephalomyelitis (EAE) and influence of allogenic brain cells on the severity of encephalomyelitis course in rats. It has been shown that the activation of microglia and macrophages of the brain is revealed in latent period after EAE induction and is kept much longer than a period of clinical disease manifestations . Encephalomyelitis severe course was accompanied by an unidirected activation of phagocytic cells in CNS and spleen. It has been demonstrated that animal new-born brain of glialenriched and neuronenriched cellular suspensions differently influenced the severety degree of EAE clinical manifestations and functional activity of phagocytic brain cells.

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ДИСЕРТАЦИЯ БЕЛЬСКАЯ.doc

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