Shevchuk N. Comparative research of antimicrobial activity and properties of new antiseptic drugs.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U000960

Applicant for

Specialization

  • 03.00.07 - Мікробіологія

04-03-2004

Specialized Academic Board

Д 64.618.01

State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine"

Essay

The thesis is dedicated to a problem of mining new antimicrobial of a medical means Palisept and investigation of antimicrobial activity of chemical combinations, which fall into to nitrones N-arilhinolilazometin. In activity conducted the microbialogic tests and the comparative analysis of antiseptic drugs of nitrones, unguentums Palisept, ET, MR. Studed velocity on speed of researches formation of a microorganisms to antimicrobial drugs. Proved that physicist-chemical characteristics of preparation stay to be stable after long keeping The express-technique of definition of components unguentum a fundamentals for a commercial production of a drug is developed. Proved experimentally antimicrobial activity of Unguentum with dekametoxin, drug of a nitrone 1. On the basis of the conducted clinical tests is proved, that a new drug antiseptic "Unguentum Palisept" shows high medical operation for ill with lesions of a skin called by a staphylococcus and a streptococcus. The obtained data allow to offer Palisept for treatment of contagions of a skin. After influence of putting an Palisept occurs healing infection skin and other areas of sick, this is characterize by reducing bacterias an staphylococcus, streptococcus.

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