Yermolayev D. Optimization of diagnostics and treatment of patients with relapses of duodenal ulcer in polyclinic

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U001255

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

30-10-2003

Specialized Academic Board

К 29.600.01

Essay

The obtained results prove that the course of duodenal ulcer at exacerbated chronic gastroduodenits is accompained by the disturbance of cellular and humoral immunity including T-cell deficiency and interleukin disbalance. The received evidence allowed to prove the urgent study of endopathis mediators of inflammation - interleukins. The growth of inflammatory IL-1b with the absence of considerable growth of anti-inflammatory IL-4 is the most unfavourable sign and the criterion of possible relapses. The complex therapy of duodenal ulcer at exacerbated chronic gastroduodenits including echinacea plant immunomodulators has a positive influence on clinical course of disease process favourse normalization of immune homeostasis and also reduces frequent relapses of duodenal ulce.

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