Savchuk G. Hematological and biochemical blood parameters under action of x-ray radiation, salts of heavy metals, and its correction by drug ersol in rat

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U003634

Applicant for

Specialization

  • 03.00.01 - Радіобіологія

12-10-2004

Specialized Academic Board

Д 26.562.01

State Institution "National Research Centre For Radiation Medicine of National Academy of Medical Sciences of Ukraine"

Essay

The object is the separate and combined action of x-ray radiation and salts of heavy metals on animal's organism, the application of the drug ersol. The aims is the research of changes in complex of haematological, cytochemical and biochemical parameters of blood in rats were investigated under separate and combined action of x-ray radiation and salts mixture of heavy metals (lead, copper and zinc). An application of biologically active drug ersol as a protector was explored. Methods - haematological, cytochemical and biochemical, light microscopy. Results - іt has been shown the research of changes in complex of haematological, cytochemical and biochemical parameters of blood in rats were investigated under separate and combined action of x-ray radiation and salts mixture of heavy metals. In animals undergoing the separate and combined action of x-ray radiation and salts of heavy metals, the application of the drug ersol preserved pathological alterations, and induced the regeneration of the changed biochemical parameters of blood. Sphere of application: radiobiology

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