Knizhenko O. Virus encephalitis at children, caused by cytomegalovirus and Herpes Simplex Virus, criteria of their differential diagnostics.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U003685

Thesis Registration Form

0404U003685.pdf

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

30-09-2004

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

Diagnostic criteria for early prognosis of clinical course in patients with bacterial meningitis and meningoencephalitis were established using of clinical, biochemical and immunological examination. The changes of T-cells, humoral and phagocytic immunity (decrease of CD3, CD4, CD8, Ig, complement, phagocytic activity of the neutrophils) were determined in meningococcal and pneumococcal meningitis and meningoencephalitis and were more expressed in pneumococcal infection. There was normalization of the majority of immunogram indices in moderate course and improvement of them in severe course during convalescence. Considerable devastation of lymphoid tissue in the thymus, spleen and lymphatic nodes with insufficiency of the macrophagal link and decrease synthesis of the IL-1 and TNF-a were revealed. Foci of destruction without development of inflammatory reaction in the brain were found in 33,3% cases of pneumococcal meningoencephalitis. DIC-syndrome was associated with decrease by synthesis of the IL-1and TNF-a.

Read more

Files

ROSDIL 1.doc

ROSDIL 2.doc

ROSDIL 3.doc

ROSDIL 4.doc

ROSDIL 5.doc

ROSDIL 6.doc

ROSDIL 7.doc

Titul.doc

USAGALNENIA RESULTATIV.doc

VISNOVKI.doc

aref.doc

Similar theses

0421U103752

Melnyk Larisa Pavlivna

Clinical and pathogenetic aspects of the combination of Lyme borreliosis, tuberculosis and giardiasis

0421U103016

Zots Yana Viktorivna

Diagnostic significance of stress-associated hormones in patients with acute bacterial meningitis

0521U101642

Shevchenko-Makarenko Olha Petrivna

Stratification of clinical-epidemiological and epigenetic factors for the personalization of management of patients with chronic viral hepatitis C

0421U102949

Shevelova Olena Volodymyrivna

Significance of the primary level of clinical, immunological and virological indicators of HIV status in predicting the effectiveness of highly active antiretroviral therapy and the risks of an unfavorable course of the disease

0421U102856

Kushnierova Olena An.

Clinical and pathogenetic features of the Epstein-Barr viral infection course in HIV-infected patients