Muzhichuk O. Substantiation and new methods of hypotensive treatment of normаl tension glaucoma

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U000253

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

17-12-2004

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Examination of patients with normal tension glaucoma revealed significant increase of the level of endothelin-1 in the blood plasma. Both the use of Betaxolol (Betoptic-S) and surgical interventions in the majority of cases resulted in a stable reduction of IOP down to tolerable degree, being accompanied by an improved visual field and a lower level of endothelin-1 in the blood plasma. Therefore it is possible to recommend hypotensive treatment of patients with normal tension glaucoma irrespective of its type, thereby alleviating the process of glaucoma.

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