Rasin O. The efficacy of suprficial-active preparation miramistine in chemical eyes burns treatment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U001351

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

18-03-2005

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Severe chemical eye burn (rabbits with the chemical eye burn model and patients with the chemical eye burns). To increase the medical treatment efficiency of patients with severe eye burns. Ophthalmological, citochemical, biochemical; biomicroscopy, fluorestsent angiography, light and electronic microscopy. Slit lamp, electronic microscope "Hitachi". For the first time the possibility of use of dehydrogenases blood neutrophiles activity changes and blood lipide products as markers of the eye burn severity and medical treatment efficiency of the alkaline eye burns were established. The new eye drops of the 0,01% miramistine solution makes it possible to active the favourable course of severe eye burning process. A new method of chemical eye burn treatment by the 0,01% miramistine solution is offered. The use of this method decrease the duration of inflammation on the 4,2 day, the area of primary cornea erosion on 6,5 mm sq, the primary cornea epithelization on 5,9 days, the frequency of recurrence erosion on 26%, and increase the frequency of the light opacity forming on 26%. Results of investigation are introduced in Filatov Institute, in the Crimean ophthalmological center in Simpferopol, Crimean medical universitete. Sphere of application - medicine, Ophthalmology.

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