Chernyavskiy V. „The significance of multi-hour esophageal pH-monitoring for diagnosis of gastro-esophageal reflux disease and evaluation of its therapeutic treatment quality”

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U002629

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

14-06-2005

Specialized Academic Board

Д 26.613.06

Shupyk National Medical Academy of Postgraduate Education

Essay

The dissertation is devoted for improvement of diagnosis and treatment of GERD. By the comparative analysis of pH-study data in GERD-patients and healthy volunteers, the normal boundary values were defined. The dependency of disease severity from esophageal acid exposure and number of reflux episodes is established. pH-monitoring indices are not dependent from patient’s age, sex, Helicobacter pylori-status and disease duration. The sensitivity and specificity of this test are on level 88,9% and 95% respectively. The test allows to evaluate the treatment efficacy objectively. Advantages of the Bravo wireless pH recording system relate to its well tolerability and high sensitivity.

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