Sameer T. Clinical and Immunological Characteristics of Pneumonia on Early-aged Children

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U002950

Applicant for

Specialization

  • 14.01.10 - Педіатрія

29-06-2005

Specialized Academic Board

Д 58.601.02

Essay

The work determines clinical and pathologically anatomic peculiarities of unfavorable course of acute pneumonia on early-aged children. It is proven that acute pneumonia on early-aged children occurs on the background of cellular and humoral immunity chains, citokinal status and adrenal system. The changes obtain reversible character and have the tendency to self-normalization on condition of favourable clinical course of the disease. The possibility is given to predict the course of disease, based on anti-inflammatory IL-1, IL-10 and Cortisole concentration evaluation. The clinical and immunological substantiation of treatment method with anti-inflammatory and immunomodulating medication Fenspirid is pursued. The demonstrations, treatment scheme and efficiency evaluating of non-specific immunomodulating therapy have been developed. Health care procedure practices the schedule of acute pneumonia treatment on early-aged children with application in therapeutic complex non-steroid anti-inflammatory andimmunomodulating medication Fenspirid.

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