Rivilis I. Factors, conducive to development peripheral neuropathy in patients with diabetes mellitus

Subject of inquiry: diabetic neuropathy in patients with diabetes mellitus (DM). Aim of inquiry: to study the prevalence of peripheral sensoriomotor neuropathy in diabetic population; risk factors of this complication development and propose the new approaches for the optimization of the treatment options. Methods of the study and equipment: anthropological, clinical, epidemiological, biochemical and statistical methods. Tuning fork Riedel-Seifert, monofilament Semmes-Weinstein, Neuropen, Thip-term, biochemical analizator Screen Master Plus. Theoretical and practical results: the data of high prevalence of diabetic neuropathy in Dniester region of Moldova was obtained. Risk factors of neuropathy development have been clarified; based on these factors allowed forming risk groups of diabetic neuropathy development for monitoring. Novelty: for the first time the prevalence in diabetic neuropathy int Dnister region of Moldova was detected, which is enlarge the epidemiologic knowledge of this complication in countries of the former USSR. The main risk factors of the development of diabetic neuropathy are the following: age, type 2 DM, duration of diabetes, unsatisfactory metabolic control and arterial hypertension. Therapeutically efficacy of thioctic acid and magned-infrared-laser therepy was shown for diminution id clinical signs of diabetic neuropathy. Practical implementation: the results of the study can be used fer early detection of diabetic patients, for monitoring of tretment efficacy and for edication of endicrinologist and GRs. Sphere of use: endocrinology, neurology.