Kutsenok V. Effectiveness of 5-aminolevulinic acid as a photosensitizer in photodynamic therapy of tumors (experimental research)

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U003882

Thesis Registration Form

0405U003882.pdf

Applicant for

Specialization

  • 14.01.07 - Онкологія

12-10-2005

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

The dissertation is devoted to the study of antitumor, antimetastatic, morphological, immunological and angiogen-dependent effects of photodynamic therapy (PDT) with the second-generation photosensitizer, 5-aminolevulinic acid (5-ALA). It has been shown that ALA-PDT effectively inhibited the growth of tumors and metastasis. These effects were accompanied by decreasing the vascular endothelial growth factor level and activation of the local and systemic immunity reactions ensues in a result of the ALA-PDT.

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Files

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ДИС.doc

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