Gorobets N. Endothelial vasoregulatory function and hemodinamical state in patients with hypertensive disease and with arterial hypertension of renal genesis"

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U004678

Thesis Registration Form

0405U004678.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

06-12-2005

Specialized Academic Board

Д. 26.613.06

Essay

It is presented the role of endothelial disfunction in patients with Hypertensive disease and chronical renal diseases. It was found decreasing of NO level more expressive in patients with Hypertensive disease and increasing of Endothelin-1 more expressive in patients with chronical renal diseases. The ET-1 coefficient (NO2 + NO3) may be used for a differential diagnostic; coefficient equal or less than 2.0 characterises Hypertensive disease, coefficient more than 2.0 - chronical renal diseases. The changes are associated with a daily profile of a blood pressure changes. endothelial disfunction influences the degree of a left ventriculum hypertrophia and is accompanied with a renal endothelial changes and the increasing of microalbuminuria.

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