Brechka N. The impact of anabolic processes stimulators held in neonatal period on somatic-sexual development of male rats

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U001174

Applicant for

Specialization

  • 14.01.14 - Ендокринологія

02-03-2006

Specialized Academic Board

Д 64.564.01

State Institution “V.Ya.Danilevsky Institute of Endocrine Pathology Problems of Academy of Medical Sciences of Ukraine”

Essay

The work is devoted to study the destruction factors of male organism sexual development pro-gram; the study of the effect of anabolic processes stimulators in neonatal period was conducted for the first time with the help of pharmaceutical agents in-jections (Retabolilum, Methyluracilum and Ribox-inum). These drugs possess ambiguous anabolic properties. As a result of the conducted research it was stated that the neonatal modulation of anabolic processes transformed the program of sexual devel-opment for adult male rats and that the nature of this transformation depended on peculiarities of the in-vestigated agents anabolic properties. It was stated also that the nature of the transformation might be exhibited by inhibition, activation and dissociation of pubertal development dynamics and functions of testicular-prostate-vesicular complex.

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