Lytvyn D. Expression of p70S6 kinase in transformed cells of epithelial origin and human endometrial adenocarcinoma

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U001748

Applicant for

Specialization

  • 14.01.07 - Онкологія

19-04-2006

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

Monoclonal antibodies against full-size p70S6K? molecule were generated and characterized. Influence of epidermal growth factor on expression and enzymatic activity of p70S6K isoforms has been studied. Patterns of expression of p70S6K isoforms upon growth of experimental tumors in vivo were determined. Patterns of expression and enzymatic activity of p70S6K in human endometrial adenocarcinoma were studied

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