Ivanushko Y. Radiation-induced changes in the rat liver and their correction by laser irradiation

The object – radiogenic changes in the liver of rats radiated with ionizing and laser irradiations. The aim is ascertaining the peculiarities of radiogenic changes in the rat liver and a possibility of their correction by means of laser radiation. Methods – biochemical, morphological, histochemical, statistical. Results – an essential influence of the fractional x-ray and laser radiations on the accumulation of the products of the oxidative protein modification during early and remote terms following radiation has been revealed. It has been demonstrated that laser radiation modifies radiogenic changes caused by the action of x-ray radiation, diminishing the intensity of changes in regard for the parameters studied under the action of previous x-ray radiation. It has been proved that laser radiation corrects radiogenic changes, induced in the rat liver at early stages following radiation, pertaining to the fibrinolytic, proteolytic activities, antioxidant defense. The radio protective action of laser radiation is evident to a greater extent. Sphere of application – radiobiology