Sorocoumova L. Antimicrobial activity and biological action of new quaternary-ammonium compounds

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U001696

Applicant for

Specialization

  • 03.00.07 - Мікробіологія

23-03-2007

Specialized Academic Board

Д 64.618.01

State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine"

Essay

The thesis is dedicated to investigation microbiological and experimental basis make use of new antiseptic preparations with decametoxine and gentamicine, "Ophtadec", "Aurisan", "Cidelone". Influence of acidity and microbial pressure on the antimicrobial activity of antiseptics medicines has been carried out. Make inquiries the investigation results of resistance formation speed for clinical isolates of staphylococci and E.coli to antiseptics medicines, have been demonstrated. Antiseptic preparations influence onto the adhesive properties of staphylococci has been studied experimentally. In animals antimicrobial medicine influence onto the structure of the eye, heart, liver, kidney tissue has been studied. Obtained results of investigation indicating to good wide use of new antiseptic medicines for prophylaxis and therapy of suppurative lesions caused.

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