Panov D. The triterpene glycosides of Kalopanax septemlobus (Thunb.) Koidz.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U002283

Thesis Registration Form

0407U002283.pdf

Applicant for

Specialization

  • 02.00.10 - Біоорганічна хімія

15-05-2007

Specialized Academic Board

Д 41.219.02

Essay

For the first time complex studying of glycoside composition of the stem bark, leaves, fruit pericarp and seeds of two varieties of Kalopanax septemlobus have been carried out. Chemical structures of 40 glycosides of beta-amyrin type were determined, 16 from them have not been found in K. septemlobus earlier (5 of these – in Araliaceae), and 13 – are new compounds. For the first time esterified glycosides containing a trans-caffeic acid in Araliaceae family and the new type of triterpene glycosides containing glucuronic acid moiety at C-28 aglycone atom were found. It was shown that the row glycosides of K. septemlobus possess high antifungal activity against pathogenic Candida albicans. Phytochemical comparative study of two varieties of K. septemlobus glycoside composition was carried out. It was suggested to raise the rank of these varieties to the self-contained species of Kalopanax genus.

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aref.doc

Диссертация--01_Введение.doc

Диссертация--02_РАЗДЕЛ 1 - Литобзор.doc

Диссертация--03_РАЗДЕЛ 2 - Экспериментальная часть.doc

Диссертация--04_РАЗДЕЛ 3 - Обсуждение результатов.doc

Диссертация--05_Выводы.doc

Диссертация--06_список использованных источников.doc

Диссертация--07_Приложение А.doc

Диссертация--08_Приложение Б.doc

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