SKRYTSKAY T. ” Clinical peculiarities of ovarian carcinoma associated with biological features of tumor tissue and level of tumor necrosis factor in blood of patients.”

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U002371

Applicant for

Specialization

  • 14.01.07 - Онкологія

16-05-2007

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

The paper demonstrates a correlation between tumor necrosis factor-? (TNF- а), p16 gene methylation, apoptosis index (AI) and clinical and morphological characteristics of noncancerous growths and ovarian cartinomas; in addition, a correlation between morphological changes in tumors of hatients with ovarian carcinoma and the factors listed above, under neo-adjuvant chemotherapy (neo-ChT), is specified more precisely; the paper also shows the possibility of their use, diagnostics and ancrease in therapy effectiveness.

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