Lajimi K. The structural functional state of the thyroid in patients with type 2 diabetes mellitus under the condition of iodine deficiency

In dissertation we have studied the structural functional state of the thyroid in patients with type 2 diabetes mellitus under the condition of iodine deficiency. Object: thyroid dysfunction and thyropathies in patients with diabetes mellitus (DM) and metabolic syndrome. The aim of work is to establish the structural and functional peculiarities of the thyroid state and their connection with clinical and biochemical indices in patients with type 2 DM and metabolic syndrome. Methods and apparatus: clinical, instrumental, US, radioimmune; analyzer “Gamma-2”, US apparatus “AU BIO-MEDIKA”, biochemical analyzer Screen master Plus. Theoretical and practical results: the connection between thyroid structure and functional state and clinical-biochemical peculiarities of type 2 DM under iodine deficiency was established. It was demonstrated that metabolic syndrome is a risk factor for the development of thyroid pathology. It was proved that the compensation of carbohydrate metabolism resulted in the improvementof conversion Т4 in Т3. The results of work show the importance of thyroid status monitoring in patients with type 2 DM and metabolic syndrome. The new: the new data connected with the frequency and character of thyropathies in type 2 DM and metabolic syndrome under iodine deficiency were obtained. A parallelism between the levels of glycosuria, glycemia and size of ioduria was revealed. The level of approach: the results can be used in timely exposure and treatment of thyroid pathology in patients with type 2 DM and metabolic syndrome. Field of application: endocrinology.