Fedorenko O. Biophysical propetries of ionnic channels from the nuclear envelope membranes.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U004465

Thesis Registration Form

0407U004465.pdf

Applicant for

Specialization

  • 03.00.02 - Біофізика

30-10-2007

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

This work is devoted to studies of general biophysical properties of ion channels from different cell types. Our researchhas shown that different types of cells express different este of ion channels in the nuclear membranes. These channels are not associated with the nuclear pore. Inositoltrisphosphate receptors were found in the inner nuclear membrane of pyramidal neurons from CA1 region of the hippocampus. So the nuclear envelope of these cells can function as Ca2+ store. We propose a new mechanism of the regulation of the Ca2+ signal in the nucleus.

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Files

a-ref.doc

dissertation.doc

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