Komarovska-Porochnyavets O. Synthesis, structure and biologycal activity of sulfo- and aminoacid derivatives of 1,4-naphthoquinone

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U001503

Thesis Registration Form

0408U001503.pdf

Applicant for

Komarovska-Porochnyavets Olena Zoryanivna

Specialization

02.00.03 - Органічна хімія

Date of defense

17-03-2008

Specialized Academic Board

Д.35.052.01

Essay

The thesis deals with the determination of synthetic methods of obtaining of aminoacid, sulfoaminoacid and thiosulfoacid derivatives of 1,4-naphthoquinone. It also covers the identification of the mechanism of biological activity dependence (antiischemic, antihypoxic, acute toxicity, antimicrobial, growth-regulating) on the constitution of researched compounds on the basis of experimental and computer screening. The methods of possible practical use of synthesized bioactive cjmpounds have been suggested.

Thesis supervisor

Novikov Volodymyr Pavlovych

Official opponents

Чирва Василь Якович
Грищук Богдан Дмитрович

Files

aref.doc

dis1-5.doc

dis10.jpg

dis6.jpg

dis7.jpg

dis8.jpg

dis9.jpg

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