Фуштей А. Klinical-pathogenetic value and medicamentous correction endothelial dysfunctions at hypertonic illness in combination with chronic obstructive lung disease

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U001750

Thesis Registration Form

0408U001750.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

22-02-2008

Specialized Academic Board

Д 29.600.01

Essay

In dissertation, on the base of complex clinically-laboratory, instrumental and radioisotope investigation of 120 patients with essential hypertension (EH), chronic obstructive bronchitis (COLD) and in their combination, the generalized data is given in relation to the role of endothelial dysfunction in the pathogenic mechanisms of left ventricle (LV) remodeling. Direct correlation dependence is set between the degrees of pulmonary insufficiency, EH and by the basal level of some pressor neurohumoral substances (adrenalin, noradrenalin, renin, aldosteron) and development of LV dysfunction (forming of eccentric hypertrophy and concentric remodelling) for patients with EH in connection with COLD. The role of cortisol is certain, as a marker of bronchial obstruction. Efficiency of combined antihypertensive therapy is proved for angiotensin converting enzyme inhibitor enalapril maleas and calcium channel blocker dilthiazem (diacordin) in relation to the improvement of the of endothelial function state, cardiohemodynamic, to regress of hypertrophy at patients with EH in combination with COLD.

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Files

10_Розділ 6.doc

11_Висновки.doc

12_ПрактРекоменд.doc

13_ ЛИТЕРАТУРА.doc

1_ ТитульныйЛист.doc

2_ПерелікУмовнихСкорочень.doc

3_Зміст.doc

4_Вступ.doc

5_Розділ 1.doc

6_ Розділ 2.doc

7_Розділ 3.doc

8_ Розділ 4.doc

9_ Розділ 5.doc

Фуштей.doc

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