Mironyuk N. The problem of iodine deficiency and its elimination in the population of Western regions of Ukraine

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U004500

Applicant for

Specialization

  • 14.01.14 - Ендокринологія

21-10-2008

Specialized Academic Board

Д 26.558.01

STATE INSTITUTE "V.P. KOMISSARENKO INSTITUTE OF ENDOCRINOLOGY AND METABOLISM OF THE NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE"

Essay

Object: iodine-deficient disturbances among Ukraine population. The aim of work: to obtain an epidemiological characteristic of iodine deficiency degree among children’s and adults population of Western regions of Ukraine, according to WHO criteria, and provide theoretical grounds to develop ways of iodine deficiency elimination. Methods of study and equipment: general clinical, instrumental, laboratory, epidemiological, statistical methods; spectrophotometer “JANWAY 6300”, ultrasound device “Scanner-100”, immunoenzymic analyzer (IEA) “Multiscan EX”. Theoretical and practical results: based on modern criteria of evaluation of iodine deficiency, the degree of iodine deficiency in children and women of Western regions of Ukraine has been established. The relationship between iodine intake and indicators of non-verbal intellect, and harmoniousness of physical development of children has been determined. A systematic monitoring of iodine intake in the population with an evaluation of the quality of preventive measures will allow for a differential approach to planning of programmes of iodine deficiency elimination on all levels. Novelty: for the first time, the degree of iodine deficiency has been evaluated in children and women of Western regions of Ukraine, based on the following indicators: urinary iodine excretion, findings of ultrasound examination of thyroid status, blood level of thyroid-stimulating hormone in new-born children. The level of table salt iodination with the purpose of mass iodine prophylaxis has been mathematically and statistically grounded, which will enable to ensure normal iodine intake and prevent iodine-induced diseases. Degree of introduction: the results of the work have been introduced into clinical practice, allowing endocrinologists to evaluate regional endemia and to plan prophylactic measures. Field of application: endocrinology, pediatrics, obstetrics.

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