Gololobova O. The system of immunoregulation and prognostic importance of its disorders in patients with HCV-infection.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U005578

Thesis Registration Form

0408U005578.pdf

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

27-11-2008

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

The role of integrated analysis of cell and secretory immunity indices, the role of immune response mediators changes in evaluation of corresponding organism reaction against HCV-infection, prognosis of severity and consequences of the disease have been shown. Immune status changes regarding virus genotype, course, replicative and biochemical activity have been analyzed. Criteria of course prognosis and outcomes of acute hepatitis C have been worked out. Optimization of pathogenic treatment including imunofan as a part of treatment in patients with hepatitis C has been substantiated considering immunological balance disorders established. Evaluation of therapeutic effectiveness and immunological characteristics of imunofan in treatment of hepatitis C has been conducted.

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Files

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