Shakun Y. Microbiological ground of perspective receipt of complex medicinal preparation in terms of prodrug with microbocidic effect

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U000193

Applicant for

Specialization

  • 03.00.07 - Мікробіологія

19-12-2008

Specialized Academic Board

Д 64.618.01

State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine"

Essay

In the dissertation on theoretical ground and experimental confirmation perspective inculcate in clinical practice medical preparations on the basis of a phenolantiseptics (prodrugs). An individual phenolantiseptics (prodrugs) use hexamethylenetetramine and phenyl salicylic as markers. It was performed ability a phenolantiseptics (prodrugs) in antimicrobial activity in the modification of pH habitat. Results of investigation have been used for choice of composition and development of technology complex antiseptic ointment "Hexaphenoxid" for treating purulent infection and burns. Chemotherapeutically efficiency complex antiseptic ointment "Hexaphenoxid". The proved expedient combination used tablets "Urobesal" and complex antiseptic ointment "Hexaphenoxid", and that fact allows using these medicine in complex schemes of anti-infectious therapy.

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