Apanasenko O. Structural and functional cardiac peculiarities in children with systemic connective tissue dysplasia

The dissertation is devoted to the improvement of early diagnosis of cardiovascular disturbances in children with systemic connective tissue dysplasia by study of results of clinical, biochemical and instrumental investigations. The facts about frequency and peculiarities of clinical manifestation in children with different degree of connective tissue dysplasia, various minor anomalies of the heart are analyzed. The morphological peculiarities of structures of the heart in patients with connective tissue dysplasia by echocardiography are determined. The character of correlation between cardiac arrhythmias and connective tissue dysplasia of the heart depending on the degree of its expression are ascertained. The criteria of early diagnosis of cardiac arrhythmias in children with connective tissue dysplasia are developed, the prediction algorithm of arrhythmias are founded. Key words: connective tissue dysplasia, minor anomalies of the heart, arrhythmia, children.