Butnytsky Y. Clinic-endoscopic data of morphological changes of the mucous of stomach and duodenal intestine in sick children with conjoint chronic pathology of the gastroduodenal and bile systems, and optimisation of their treatment

Dissertation is devoted to the study of the clinic-endoscopic specifics, morphologic, morpho-metric and immuno-morphologic changes of the mucous of stomach and duodenal intestine in sick children with conjoint chronic pathology of the gastroduodenal and bile systems resulting from infection with Helicobacter pylori, before and after treatment and optimisation of anti-helicobacterial therapy by the means of ozonized sea-buckthorn oil. It is determined that in children, who additionally to their treatment were prescribed ozonized sea-buckthorn oil, a convincing increase in flow-allowing capacity of micro arteries of the stomach has been observed, that as a result led to improvement of blood circulation in the mucous. Therapeutic use of the ozonized sea-buckthorn oil helped to achieve significant fall down in the level of inflammatory reactions. Statistically significant decrease in the amount of IgM and IgG plasmatic cells proves the situation as well. Based on the obtained data a clinic-endoscopic table has been drawn up, which allows to prognosize, by the obtained diagnostic criteria, presence of the Helicobacter pylori in children. The method of determination of integral index of tissue regeneration is developed for the evaluation of the conducted medical treatment efficiency.