Volskiy Y. Eficacy of standard regimens of chemotherapy in retreatment patients with pulmonary tuberculosis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U004599

Applicant for

Specialization

  • 14.01.26 - Фтизіатрія

28-09-2009

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research - newly detected previously treated pulmonary tuberculosis, relapses; the purpose - improvement of efficacy of treatment of previously treated patients with newly detected tuberculosis and relapses on the basis of development standard regimens of chemotherapy by study of prevalence of drug resistance of MBT among these patients; methods - clinical, X-ray, microbiological, biochemical, statistical; the novelty - it was established the rate of drug resistance and risk groups among previously treated tuberculosis patients; developed standard regimens of chemotherapy for 4 category allowed on 27,9 % to increase efficiency of treatment results in previously treated patients on the parameter of the sputum conversion and to decrease the rate of side effects on 15,7 % and treatment cost in 1,6 fold.

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