Ponomaryova I. Disturbances it is immunity system and microbiocenosis of intestinal in children, sick with enterocolitis, and their correction by probiotiks

Results to manuscript testify that immunity status in children, sick with enterocolitis is characterized by the unbalance of the level T of helpers and T- cytotoxic lymphocytes, decrease in the level CD25+ and CD95+ lymphocytes of the blood, which tells about of selective immune insufficiency with enterocolitis.There are observed essential disturbances in the mucosa immunity of bowels, namely in the mechanisms of synthesis and transport of the secretory of IgA, against the background the haick level of IgG and IgM. The application of probiotikterapy with the determination of the individual sensitivity of conditional-pathogenic microflora to probiotiks contributes to strengthening the function T of the cellular component of immunity, that is manifested in an increase in the blood of level CD3+, CD4+ lymphocyte and reduction in the concentration CD8+ and CD95+ lymphocytes, and also the normalization of the phagocytic activity of neutrophils. The carried out treatment has positive influence on the local immunity, about that testifies an increase in the secretory of IgA in coprofiltraty and to the indices of microbiocenosis of intestinal.