Kalyn T. Synthesis and reactions of 1,8-dioxopolyhydroaсridines

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U000708

Thesis Registration Form

0410U000708.pdf

Applicant for

Specialization

  • 02.00.03 - Органічна хімія

22-02-2010

Specialized Academic Board

Д 35.052.01

Lviv Polytechnic National University

Essay

The thesis is devoted to a research of synthesis of 1,8-dioxopolyhydroaсridines and their chemical transformation. It was discovered for the first time that heterocyclization of bis-dimedonilalkanes and anilines with electron-donor substitutes leads to formation of octahydroacridines without alkyl substitutes in position 9. It is determined that condensations of carbonyl groups decahydroacridin-1,8-diones with nucleophiles carry out with saving 1,4-dihydropyridines fragment. Photostable and photosensitive substances and the substances with antimicrobial activity are discovered among the synthesized compounds.

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Files

dis.doc

аref.doc

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