Sami S. Experimental end clinical substantiation correction of processes neutralisation of reactiv oxygen forms in crystal lens at cataractogenesis.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U003511

Thesis Registration Form

0410U003511.pdf

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

21-05-2010

Specialized Academic Board

К 26.613.05

Essay

In this work the state of enzyme antioxidant system of the lens in experimental cataract and the different clinical stages of senile cataracts were studied. It was learned the effect of Thiotriazolin (TTA) on the level of violations of antioxidant enzymes. We proved that the activity of the antioxidant enzyme system was more significantly reduced (p <0,001) in subcapsular and mixed senile cataract: superoxidedismutase - on 60,0% - 69,8% and catalase - on 40,0% - 49,6 %, respectively. On the data of experimental, clinical and biochemical studies it was revealed that TTA can reduce the negative impact of light energy on the degree of aggregation of protein molecules, the level of chromogen, the level of fluorohenive and biophysical indicators. It was proved that TTA benefits stabilizing and stimulating effect on the antioxidant enzyme system in senile and in experimental (in vitro and in vivo) cataract.

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Files

aref - 0.doc.doc

aref - titul.doc

Диссертация Сами С.Ю. Альсаиди 5.doc

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